Doctors said, on Friday, in a review of reports on Corona patients, that the virus not only damages the lungs, but its complications affect the kidneys, liver, heart, brain, nervous system, skin and digestive system.
The team at Irving Medical Center at Columbia University in New York City, a hospital flooded with patients in the spring, have had their own experiences collecting reports from other medical teams around the world.
The overall picture of the virus shows that it attacks almost every major system in the human body, resulting in direct organ damage and causing blood clotting, heart loss for a healthy rhythm, kidneys to spill blood and protein, and skin rashes.
It also causes headaches, dizziness, muscle and stomach pain and other symptoms, along with classic respiratory symptoms, such as coughing and fever.
"Doctors need to think of Covid 19 as a multi-system disease ... There is a lot of news about thrombosis, but it is also important to understand that a large percentage," Dr. Akriti Gupta, a Colombia cardiologist fellow who participated in the evaluation work, said in a statement. Of these patients, kidney, heart, and brain damage, and doctors need to treat these conditions along with respiratory disease.
Much of the damage caused by the virus appears to come due to its affinity with a receptor - a type of molecular inlet in cells - called ACE2.
The cells lining the blood vessels in the kidneys, the liver channels, the pancreas in the intestine and the lining of the respiratory tract are all covered with ACE2 receptors, which the virus can use to interact with and infect cells, as the Columbia team wrote in its review published in Nature Medicine.
"These results indicate that infection of multiple organs may occur at least in part, due to direct viral tissue damage," the team wrote.
Dr. Mahesh, another fellow cardiologist who worked on the review, said in the statement: "This virus is unusual, and it is difficult not to step back a step back and not be surprised by the number of evidence that appears on the human body."
It appears that the effects of blood clotting are caused by several different mechanisms: direct damage to the cells lining the blood vessels and interference with different blood clotting mechanisms in the blood itself. The researchers said that low oxygen in the blood caused by pneumonia could make the blood more prone to thrombosis.
These clots can cause strokes and heart attacks, or they can sit in the lungs or legs. It can also block the kidneys and interfere with dialysis treatments necessary for patients.
Corona virus can damage the pancreas and worsen diabetes. Diabetics have been shown to be at greatest risk of severe disease and death from corona virus.
The virus can also damage the brain directly, but some neurological effects may come from treatment.
The effect of corona extends to the immune system, where it depletes cells that the body normally circulates to fight viral infection.
The Irving Medical Center team at Columbia University said that doctors need to treat all these effects when Corona patients appear in the hospital.
However, there is some good news. "The symptoms of the digestive system may be associated with a longer period of disease but have not been associated with increased mortality ... and many skin effects, such as purple and purple rashes, and swollen fingers, also appear on their own," the researchers wrote.
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